Social Information Processing in Teens (SIP Study)

Primary Objective

Clinically significant, chronic irritability is a major dimension of child and adolescent mental health problems. A promising way to treat irritability is to address negative biases. Irritable youth tend to misjudge neutral or ambiguous social signals. By understanding how clinically irritable youth make these interpretations, we may develop new diagnostic tests and refine treatments for them.

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Interested in how irritability affects social information processing in teens? Our goal is to learn more about how people commonly react to social ambiguity and how irritable mood may relate to negative interpretations of social signals in adolescence.

Main Procedures Involved: Participation involves a single 2.5 hour study visit. Both the teen and a caregiver will complete interviews and questionnaires. The teen will also complete tasks while in a magnetic resonance imager (MRI). Study visits will be onsite at the Anschutz Medical Campus. Compensation is provided.


13 to 17 years


Your child may be eligible if: �� 13-17 years old �� Currently in mental health treatment �� No serious medical conditions

Inclusion Criteria ■ Adolescents ages 13 to 17 years in mental health treatment, ranging from low to high, clinically significant irritability. Exclusion Criteria Any of the following mental health diagnoses: ■ current post-traumatic stress ■ lifetime bipolar I or II disorder ■ lifetime cyclothymic disorder ■ lifetime psychotic disorder ■ lifetime autism spectrum disorder ■ Major medical problems, including head trauma ■ MRI-specific safety exclusions ■ Clinical instability

Type of Study





Compensation Provided

Principal Investigator
Photograph of Tara Trujillo

Tara Trujillo

Study ID

Protocol Number: 20-2633

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