Contraceptive Hormone and Reward Measurement (CHARM Study)

Primary Objective

Our research team is investigating how oral hormonal contraceptives affect the brain and emotional wellbeing.

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The study is examining the effects of hormonal oral contraceptives (OCPs) on brain processes and emotional wellbeing. Study participants will: Participate in 3 study sessions, one online and two in-person, over the course of 2 months. Complete interviews and questionnaires Taking an FDA approved oral contraceptive medication or placebo for 21 days. 2 brain imaging sessions 2 blood draws Compensation will be provided for participation in the research study.




You may be eligible if you are: A woman or assigned female at birth Between 18-45 years old Right-handed Not taking hormonal birth control Having regular periods

Type of Study





Brain Imaging Center (BIC)
Outpatient CTRC

Principal Investigator
Photograph of Andrew Novick,  MD, PhD

Andrew Novick, MD, PhD

Study ID

Protocol Number: 21-3530

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