Effect of Alkali Therapy on Vascular and Graft Function in Kidney Transplant Recipients

Is this Study for You?

Let's Get Started!


Participation will last approximately 52 weeks and will include 3-7 in-person visits. Baseline, Month 6, and Month 12 visits will be held in person to assess blood vessel health. Baseline visits will be coordinated with patients' 1 year post-transplant biopsy. The Month 12 biopsy will occur for study purposes outside of standard of care. 24hr urine samples will be collected at Baseline and Month 12. Month 1, 3, and 9 visits can be conducted remotely to check safety labs and complete questions via phone. Blood pressure, weight, health, and medication changes will be assessed throughout the study.




-Age 18-80 years -Kidney transplant received 1 year prior to randomization into study -Kidney function of >/= 45 ml/min/1.73m2 (Using CKD-EPI eGFR equation) -Carbon dioxide blood levels of 16-24 mEq/L

Type of Study



Renal Research Center
University of Colorado Hospital

Principal Investigator
Photograph of Jessica Kendrick,  MD

Jessica Kendrick, MD

Study ID

Protocol Number: 21-3447

More information available at ClinicalTrials.gov: NCT05005793

Is this Study for You?

Let's Get Started!

Not finding the right Study for you? Join ResearchMatch, a nation-wide registry connecting volunteers and researchers