Skeletal Response to Simulated Night Shift (SPOTLIGHT Study)

Primary Objective

We are looking for healthy men & women to study the effects of sleep disruption on bone. Please click on the "Let's Get Started!" button below to determine your eligibility.

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What is involved: • Measurements of bone mineral density • Completion of sleep questionnaires/assessments • Randomization to sleep with a simulated night shift schedule or normal sleep schedule • A general physical exam • Activity monitoring with a wrist monitor • Blood/urine collection • Arterial line placement • Two 4-night inpatient stays

Duration of Participation: Your participation in the study will last up to 6 weeks (including two 4-night inpatient stays).


20 to 40 years


You may qualify if you are 20-40 years old, habitually sleep 7-9 hours per night, haven't done night shift work in the past year, and do not currently smoke.

Type of Study

Outcomes Research




You will receive up to $1,500 and a FitBit for your time.

Principal Investigator
Photograph of Christine Swanson,  MD, MCR

Christine Swanson, MD, MCR

Study ID

Protocol Number: 20-3013

More information available at NCT05074277

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