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Sex Hormone and Vascular Function in Women with CKD: A Cross-Sectional Study

Primary Objective

This research study will compare sex hormone concentrations in healthy women to women with chronic kidney disease. We also measure blood vessel function using non-invasive testing. Participation will consist of one screening visit (approximately an hour) and one testing visit (approximately 3 hours of time or less). The testing visit will include non-invasive testing of blood vessel function. Testing takes place at the University of Colorado Anschutz Medical Campus.

Study

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Description

This research study will compare sex hormone concentrations in healthy women to women with chronic kidney disease. We also measure blood vessel function using non-invasive testing. We are looking for: ? Women ? Aged 18-44 OR 55-75 years ? Generally healthy and free from hypertension OR Have Chronic kidney disease (CKD) ? Non-smokers ? Free from advanced CKD requiring chronic dialysis ? Women must not take an oral contraceptive or not use oral hormone replacement therapy ? Women must not be pregnant or trying to become pregnant

Main Procedures Involved: - Blood draw - Non-invasive vascular testing

Duration of Participation: Participation will consist of one screening visit (approximately an hour) and one testing visit (approximately 3 hours of time or less).

Details
Age

Eligibility

 Women  Aged 18-44 OR 55-75 years  Generally healthy and free from hypertension OR Have Chronic kidney disease (CKD)  Non-smokers  Free from advanced CKD requiring chronic dialysis  Women must not be pregnant of trying to become pregnant

Type of Study

Observational

Scope

Local

Compensation

$50

Location

University of Colorado Hospital

Principal Investigator
Ester Oh

Ester Oh

Resources

Study ID

Protocol Number: 21-3018

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