Participate in Research at CU Anschutz

Adult

i. Inclusion criteria for all participants: A) Between 21 and 65 years of age, and B) can understand the nature of study and can sign an informed consent document. ii. Inclusion criteria for AUD group: A) recently admitted to the Center for Dependency, Addiction, and Rehabilitation (CeDAR). iii. Inclusion criteria for healthy comparison group: We will recruit adults without a history of alcohol use disorder who resemble patients at CeDAR during the prior year in terms of age, sex, and socioeconomic status distributions. iv. Exclusion criteria for all participants: A) positive result on urine drug screen or breathalyzer at the start of any study visit, B) inability to complete MRI (e.g. presence of ferromagnetic objects in body), C) current use of medications that alter the hemodynamic response, such as insulin, D) history of trauma resulting in loss of consciousness longer than 15 minutes, E) currently experiencing withdrawal from alcohol as indicated by a CIWA-Ar score greater than 8 (Sullivan, Sykora et al. 1989), F) diagnosis of bipolar disorder or schizophrenia, G) past 48-hour use of drugs to treat alcohol withdrawal (e.g. benzodiazepines), H) Clinician-Administered PTSD Scale for DSM-5 score >3 (e.g. severe and incapacitating), and I) for females, pregnancy. v. Exclusion criteria for healthy group: A) History of a substance use disorder (lifetime or current).