Participate in Research at CU Anschutz

This study looks at the relationship between cardiac health and exercise capacity between men and women with and without type 2 diabetes (T2D). In addition, the study identifies differences in how exercise training effects the heart, bloods vessels, and metabolism in men and women with and without T2D, to help identify specific differences in their response to exercise training. The study will recruit a total of 40 participants from the Denver area (20 people with T2D and 20 overweight control subjects).

Participants will undergo baseline testing of their heart, blood vessel, and skeletal muscle function, and perform tests to determine exercise ability. Participants will then do exercise training for 15 weeks, and all testing will be repeated.

Main Procedures Involved: Exercise testing includes cardiac and muscular ultrasound, exercising on a stationary bicycle while measuring oxygen use, and tests of how well your body uses sugar, as well as muscle biopsy, and Magnetic Resonance Imaging.

Duration of Participation: Approximately 7-8 months