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ALZHEIMER'S CLINICAL TRIAL CONSORTIUM FOR DOWN SYNDROME (ACTC-DS) TRIAL-READY COHORT - DOWN SYNDROME (TRC-DS)

Primary Objective

Aim 1: To enroll 120 non-demented adults with DS (ages 35-55) across 15 sites into the TRC-DS. Aim 2: To determine longitudinal cognitive, clinical and biomarker trajectories in the TRC-DS.

Study category: Brain and Nervous System

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Description

TRC-DS is part of a larger movement working with people with Down syndrome to advance Alzheimer's disease therapies and potential cures for this population. The Alzheimer's Clinical Trials Consortium-Down Syndrome (ACTC-DS) is a large collaboration of researchers conducting clinical trials for Alzheimer's disease in people with Down syndrome. The University of Colorado has partnered with the ACTC-DS to participate on the Anschutz Medical Campus. TRC-DS is the first of these studies and has the goal of creating a group of eligible volunteers with Down syndrome who are interested in participating in future clinical trials.

Details
Age

Adult

Eligibility

Are healthy adults, between ages 35-55, with Down syndrome; Have an interest in participating in clinical research; Will visit the University of Colorado Linda Crnic Institute once every 16 months for routine exams and brain scans.

Type of Study

Registry

Scope

National

Locations

Outpatient CTRC
University of Colorado Hospital

Principal Investigator
Joaquin Espinosa,  PhD

Joaquin Espinosa, PhD

Study ID

Protocol Number: 20-2692

More information available at ClinicalTrials.gov: NCT04165109

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