Effect of Hormones on Frequency of Headache and Brain Structure and Function in Puberty
We are doing this study to learn more about the effects of hormones on headache, brain structure and function. We are enrolling some people starting a medication called estradiol as well as some people not starting any hormone medication.
This research studies how hormones impact headache and how different parts of the brain talk to each other
Main Procedures Involved: This study may involve 2 MRI scans, which is a safe method of looking at the structure and function of the brain. There are also 2 visits with a blood draw, questionnaires, headache interview, and physical exam. Participants will keep a daily headache diary for 1 year.
Duration of Participation: Participation in this study lasts approximately one year.
11 to 20 years
Jennifer Hranilovich, MD
Protocol Number: 20-1824
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