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Brigatinib Before Brain Irradiation Trial (B3i Trial): A Phase II Trial of Brigatinib Alone for Brain Metastases from ALK+ Lung Cancer

Study category: Cancer

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II - Research Studies that gather preliminary data on whether a drug works in people who have a certain condition/disease (that is, the drug's effectiveness). For example, participants receiving the drug may be compared to similar participants receiving a different treatment, usually an inactive substance (called a placebo) or a different drug. Safety continues to be evaluated, and short-term adverse events are studied.

Type of Study



City of Hope Cancer Center
University of Colorado Hospital

Principal Investigator
Chad Rusthoven

Chad Rusthoven

Study ID

Protocol Number: 19-2862

More information available at NCT04634110


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