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Bicarbonate Administration and Cognitive Function in Midlife and Older Adults with CKD

Study category: Kidney Disease & Hypertension

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This study is a 52 week intervention with visits at the CU Med Building on the Anschutz Medical Campus. Visits will include blood pressure checks, blood and urine collection, measurement of brain blood flow, measurement of cognitive function, and assessment of physical function via a questionnaire.



-Able to provide consent -Age 50-70 years -CKD stage 3b-4 with eGFR of 15-44 -Blood pressure <140/90 prior to randomization

Detailed Eligibility: -No history of stroke -No history of dementia -No history of neurologic disease


Pilot - A pilot Study is used to obtain information, and work out the logistics and management, deemed necessary for further Research Studies.

Type of Study



Renal Research Center

Principal Investigator
Jessica Kendrick,  MD

Jessica Kendrick, MD

Study ID

Protocol Number: 20-1672

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