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A Phase I study of the ADAM-10 inhibitor, INCB007839 in children with recurrent/progressive high-grade gliomas to target microenvironmental neuroligin-3

Study category: Cancer

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Child to Adult


I - Research Studies that focus on the safety of a drug. The goal is to determine the drug's most frequent and serious adverse events and, often, how the drug is broken down and excreted by the body. These studies usually involve a small number of participants.

Type of Study



Childrens Hospital Colorado

Principal Investigator
Kathleen Dorris

Kathleen Dorris

Study ID

Protocol Number: 20-1487

More information available at NCT04295759


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