The early and late contribution of fasting and postprandial triglycerides on newborn subcutaneous and intrahepatic fat in pregnancy

Primary Objective

This study aims to prospectively define the role of maternal triglycerides as an important unrecognized contributor to both newborn subcutaneous and intrahepatic fat in overweight and obese (OW/OB) mothers in a community setting.

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What Happens If I Join the Study? - You will have 4 study visits during pregnancy and 1 study visit after your baby is born - You will be asked to prick your finger to monitor blood sugar and blood triglyceride levels 4 times a day for 4 days after each visit (total of 64 finger pokes) - We will measure you and your infant’s body composition at about 1-2 weeks of life - You will be asked to complete several questionnaires about your pregnancy and general health - Financial compensation for participation will be given


Child to Adult


Who Can Join the Study? - Highly motivated pregnant women who: - Are between 21-39 years old - Are less than 16 weeks pregnant - Are willing and able to complete home blood tests - Do not have gestational diabetes or high blood pressure - Are nonsmokers

Type of Study





Broomfield Hospital
Cherry Creek Medical Center
Childrens Hospital Colorado
CTRC Inpatient
Highlands Ranch Hospital
Lone Tree Medical Center
Longs Peak Hospital
Outpatient CTRC
UCHealth Central Park Medical Center
UCHealth Internal Medical Clinic - Lowry

Principal Investigator
Photograph of Linda Barbour,  MD

Linda Barbour, MD

Study ID

Protocol Number: 20-0706

More information available at NCT04394806

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