Effects of prenatal antibiotics on the infant gut microbiome

Three different bacteria of the infant gut microbiome will be obtained through collection of infant stool samples at birth and at 6 weeks of age. These bacteria will be measured and comparisons made between infants whose mothers took antibiotics during pregnancy and infants whose mothers did not take antibiotics during pregnancy. Pregnant women will be recruited between their 35-37th weeks of pregnancy and will complete two surveys, the first prenatally and the second at 6-weeks postpartum.
MoreChild to Adult
Pregnant women between 18-34 years old
Inclusions: -Singleton pregnancy -Pre-Pregnancy BMI of 18.5 - 25 -Documented negative GBS test Exclusions: -Gestational diabetes or Type I/Type II diabetes -Pre-Eclampsia -History of prior c-section or a planned c-section -History of alcohol, drug, or tobacco use in pregnancy -Do not plan to breastfeed
Observational
Childrens Hospital Colorado
University of Colorado Hospital

Sunah Hwang, MD, PhD, MPH/MSPH
Protocol Number: 19-2288
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