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Effects of prenatal antibiotics on the infant gut microbiome

Study category: Infant Care

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Description

Three different bacteria of the infant gut microbiome will be obtained through collection of infant stool samples at birth and at 6 weeks of age. These bacteria will be measured and comparisons made between infants whose mothers took antibiotics during pregnancy and infants whose mothers did not take antibiotics during pregnancy. Pregnant women will be recruited between their 35-37th weeks of pregnancy and will complete two surveys, the first prenatally and the second at 6-weeks postpartum.

Details
Age

Child to Adult

Eligibility

Pregnant women between 18-34 years old

Detailed Eligibility: Inclusions: -Singleton pregnancy -Pre-Pregnancy BMI of 18.5 - 25 -Documented negative GBS test Exclusions: -Gestational diabetes or Type I/Type II diabetes -Pre-Eclampsia -History of prior c-section or a planned c-section -History of alcohol, drug, or tobacco use in pregnancy -Do not plan to breastfeed

Phase

Not Applicable - Describes studies without FDA-defined phases, including studies of devices or behavioral interventions.

Type of Study

Observational

Locations

Childrens Hospital Colorado
University of Colorado Hospital

Principal Investigator
Sunah Hwang

Sunah Hwang

Study ID

Protocol Number: 19-2288

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