MEASURES OF PULMONARY MORBIDITY IN CHILDREN WITH DOWN SYNDROME

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Description

This study plans to learn more about lung health in children with Down syndrome. Sometimes children with Down syndrome breathe food or liquids into their lungs, which is called aspiration. We want to learn more about how aspiration affects the lungs and quality of life of children with Down syndrome. This will help us develop new treatments to protect the lungs. If you join the study, your child will participate in one or two study visits at Children's Hospital Colorado at Anschutz Medical Campus. The study procedures will take about 3 hours total, but can be spaced out to occur before, during, or after regular clinic appointments, or at a research-only visit. All of the study visit procedures are for research only. All of the study visit procedures are routinely performed in clinical care of children. The procedures include six-minute walk test, breathing test called oscillometry, exhaled nitric oxide test, and a blood draw.

Details
Age
Child
Eligibility
-Children ages 3 to 18 years old -Diagnosis of Down Syndrome/Trisomy 21 or mosaicism -Able to walk -Has had a swallow study (videofluoroscopic swallow study or fiberoptic endoscopic evaluation of swalling) performed within the past two years
Locations

Childrens Hospital Colorado

Principal Investigator
Photograph of Emily DeBoer

Emily DeBoer

Study ID

Protocol Number: 19-2092

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