Participate in Research at CU Anschutz

Child

You/Your patients may qualify for this first of its kind study if they: **Are age 12 and up. **Have severe asthma as defined by commonly accepted guidelines. **Currently have uncontrolled asthma, or worsening asthma & attacks. **Are on a stable regimen of asthma medications. **Are not pregnant and not breastfeeding. **Are not taking part in other clinical trials.For Providers: I. Inclusion Criteria: 1). 12 years of age and older 2). no change in asthma medications for the past 2 months and use of medium or high dose inhaled corticosteroids + an additional asthma controller/biologic 3). Baseline poor or uncontrolled asthma defined by: o FEV1 <80% predicted (adults over 18yrs) or FEV1 <90% (pediatric patients <18yrs) AND with 12% reversibility o Greater than or equal to 1 exacerbation, documented burst of systemic corticosteroids in prior year o Evidence of asthma by either bronchodilator reversibility or methacholine responsiveness II. Exclusion Criteria: 1). Receiving one or more immune-modulating therapies for disease other than asthma 2). < 35 weeks of gestation age 3). Requirement for daily systemic corticosteroids above 10 mg or prednisone (or equivalent) per day for the past 2 months 4).other chronic lung conditions or chronic medical conditions