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Impact of Fever Prevention in Brain Injured Patients (INTREPID)
University of Colorado Hospital Patients randomized to the fever prevention group will have ArcticGel Pads placed on their body. These will be connected to the Arctic Sun System. The system will be programmed to keep the patient's body temperature at 98.6. Treatment will last for 14 days or until ready to be discharge... |
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Surgical or Medical Treatment for Pediatric Type 2 Diabetes
Childrens Hospital Colorado, University of Colorado Hospital Surgical or Medical Treatment for Pediatric Type 2 Diabetes (STOMP-T2D) is a prospective, open-label, controlled clinical trial funded by the National Institutes of Health for a period of 5 years. We propose to study 90 participants who are 13-19 years of age and have type 2 diabetes (T2D)... |
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The use of thoracic epidural, paravertebral nerve blockade and video-assisted intercostal nerve cryoablation for postoperative analgesia after minimally invasive repair of pectus excavatum
Childrens Hospital Colorado The study is to learn more about treating pain after having a minimally invasive repair of pectus excavatum while randomly assigning different pain methods that are typically used for this procedure.... |
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Optimizing pulsatility during cardiopulmonary bypass to reduce acute kidney injury: Prospective Observational Study
University of Colorado Hospital Blood, urine, and bone marrow will be collected to analyze biomarkers of acute kidney injury risk. Sublingual microscopy will be used to collect images in the mouth. This is to study the following aims: Aim 1: Determine the effect of pulsatility during CPB on endothelial function. We wil... |
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Phase I clinical trial utilizing direct peritoneal resuscitation in liver transplant recipient population at increased risk of return to the operating room and early allograft dysfunction.
University of Colorado Hospital This study is being conducted to assess the safety of Direct Peritoneal Resuscitation (DPR) in high-risk liver transplant patients. The investigators want to also identify if this method of recovery after large surgery has the same benefits in liver transplant patients as have been appreci... |
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Understanding How Sleep Health Affects Recovery from Adolescent Concussion
Boulder Health Center, Childrens Hospital Colorado We will conduct a prospective cohort study, with two groups (concussed and control). They will undergo an initial assessment (within 14 days of concussion) and a follow up ~28 days post-concussion. Controls will follow a similar timeline. During the ~two-week period between Visits 1 & 2, p... |
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DEFIANCE: ClotTriever vs. Anticoagulation for DVT
Department Specific Free Standing Clinic, Highlands Ranch Hospital, University of Colorado Hospital This study is a prospective, multicenter, randomized controlled trial of an interventional strategy using the ClotTriever System to achieve and maintain vessel patency (ClotTriever Intervention Arm) versus conservative medical management using anticoagulation therapy alone (Conservativ... |
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Improving patient-centered Ob-Gyn care for Black women: Co-designing solutions to mitigate systemic racism, discrimination and bias
Department Specific Free Standing Clinic, University of Colorado Hospital CU OB-Gyn providers are committed to addressing racial inequities in healthcare. We invite patients, advocates and members of the community who identify as Black, African American, African, Afro-Latinx or Afro-Caribbean to share your experiences and feedback, especially those that have rec... |
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Postoperative Utilization of Incentive Spirometry with and without Electronic Patient Reminders
University of Colorado Hospital All eligible patients arriving to the PACU every day will be provided with a Vyaire Medical's AirLife volumetric incentive spirometer and instructions to perform 3 IS breaths every 20 minutes until discharge from PACU. The IS device will be set up with the breath volume considered adequate... |
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CLEAN-PE: A Prospective, Multicenter Study to Evaluate the Safety and Efficacy of an Aspiration Thrombectomy System in Acute Pulmonary Embolism
Outpatient CTRC, University of Colorado Hospital Prospective, single-arm, multicenter study. Approximately 125 subjects will be screened for 105 enrolled at up to 15 investigational sites in the United States.... |
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Perioperative Informatics of Colorado (PICO) Database
University of Colorado Hospital The development of this database will allow us to study various aspects of care provided by members of the Department of Anesthesiology at the University of Colorado School of Medicine (CU-DOA) and their association with perioperative outcomes or hospital resource utilization. The informat... |