This study wants to learn about the best way to take pictures of unborn babies' hearts to better identify certain heart health problems.
Aim 1: Test the effectiveness of Rehabbing with Peloton on physical activity as measured by daily steps. Aim 2. Examine the effectiveness of Rehabbing with Peloton on secondary health outcomes. Aim 3. Assess the implementation of the Rehabbing with Peloton using the Reach, Effectiveness, Adoption, Implementation, and Maintenance Framework (RE-AIM).
Evaluate the safety and efficacy of the Cleaner™ Pro Thrombectomy System for aspiration thrombectomy in patients with acute pulmonary embolism (PE).
The purpose of this study is to understand how shift work impacts heart health in women.
To compare the 1-year cumulative incidence of severe GVHD (from day of HCT) defined as Grade III-IV acute GVHD (aGVHD) and/or chronic GVHD (cGVHD) that requires systemic immunosuppression and to compare the disease free survival (DFS) (from time of randomization) in children and young adults (AYA) with acute myeloid leukemia (AML), acute lymphoid leukemia (ALL), and Myelodysplastic Syndrome (MDS) ...
The primary study objective is to compare the clinical outcomes of patients treated with an interventional strategy using the ClotTriever System to achieve and maintain vessel patency (ClotTriever Intervention Arm) versus conservative medical management using anticoagulation therapy alone (Conservative Medical Management Arm) in the treatment of symptomatic unilateral iliofemoral DVT
To determine the effect of abnormal menstruation on markers of cardiovascular disease in adolescent athletes.
The primary objective of this Phase I open-label study is to assess the safety and tolerability of CD19x22 CAR T cells in pediatric patients with R/R B-ALL.
This study plans to test whether oral acetate supplementation is effective at improving artery function and stiffness in healthy adults over 50 years of age.
Phase 1: To determine the recommended phase 2 dose (RP2D) of vorinostat in children, adolescents and young adults following allogeneic HCT. Phase 2: To determine the incidence of grade 2‐4 acute GVHD by day +100 in subjects who receive vorinostat in addition to standard GVHD prophylaxis after allogeneic BMT.
To evaluate the efficacy of treatment with EDIT-301 in adult and adolescent subjects with severe sickle cell disease (SCD).
Preserving endothelial function with pulsatility during CPB will be associated with less AKI after cardiac surgery.
In this research we will learn more about blood clotting and drugs that modify blood clotting.
To determine if the chronic administration of riociguat improves exercise hemodynamic profiles measured by tight heart catheterization (RHC) - in patients with subjective exercise limitation at least 6 months post-PTE surgery.
To test CAR T cell therapy (a type of therapy made from one's own immune cells) for refractory lupus nephritis
The primary objective of the BISON-PRO Database is to establish a prospective repository of real-world, longitudinally-collected patient-reported outcomes (PRO) and quality-of-life data for patients with both malignant and non-neoplastic blood disorders to support patient-centered research.
