This study is looking at how well a new drug called GS-5718 works for people with Cutaneous Lupus Erythematosus (CLE), with or without systemic lupus. We want to see if it helps reduce rashes and sores and if people can take it without a lot of side effects.
This study is testing a new treatment called CAR T cell therapy to see if it’s safe and works well for people with rheumatoid arthritis (RA). It uses a person’s own immune cells to help fight disease. In this study, a type of cell called regulatory T cells (Tregs) will be genetically modified into CAR Tregs (called SBT777101) to see if they are better at reducing inflammation in people with RA.
This study wants to see if avacopan is safe and works well for people with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. We also want to find out if it helps prevent the disease from coming back.
This study is testing a new injectable medication called anifrolumab to see how safe and effective it is for adults with chronic cutaneous lupus erythematosus (CLE). Our goal is to find better treatments for people living with CLE.
This study is looking at a medicine called Upadacitinib to see if it is safe and helps adults with moderate to severe lupus (SLE). We want to compare it to a placebo (a pill with no medicine) to see how well it works. We also want to find out how much of the medicine is needed to keep symptoms from getting worse.
In this study we want to learn more about the effects of the study drug, benralizumab, for treating children with eosinophilic granulomatosis with polyangiitis (EGPA).
This study will test if adding a new medicine called VIB4920 to regular lupus treatment can help people with lupus nephritis (a kidney problem caused by lupus) feel better. It will also check if this new medicine is safe.
Researchers are testing a drug called IMVT-1402 to see if it is safe and if it helps people with skin lupus (a type called subacute or chronic cutaneous lupus) with or without lupus that affects the whole body.
We are doing this study to see if a medicine called anifrolumab is safe to use in adults with systemic sclerosis. We also want to find out if the medicine helps with disease symptoms and if it stops the disease from getting worse.
This study will look at how well an injectable treatment works for people with detectable levels of HIV who are taking oral antiretroviral therapy (ART). This study will also check if the treatment is safe, how long it lasts, and ask about people’s experience.
We want to find out how well the medicine Belimumab works in real life for adults who have active lupus nephritis. This study also wants to see if belimumab helps keep the kidneys healthy for a long time.
We are looking for adults to join a national study to help us learn more about how rheumatoid arthritis (RA) develops.
This study wants to find better treatments for people with autoimmune diseases like rheumatoid arthritis (RA). By studying the different types of cells found in people with RA, researchers can learn more about how RA damages joints.
This study wants to see if gut problems are worse in HIV+ men that have sex with men that have metabolic syndrome compared those without metabolic syndrome.
This study is looking at whether a type of special antibody called broadly neutralizing antibodies (bNAbs) is safe to use along with antiretroviral therapy (ART) in people who have been recently diagnosed with HIV. We also want to find out if these antibodies help control HIV better after people stop their regular medicine (ART), compared to those who didn’t get the antibodies.
To longitudinally study individuals at risk for spondyloarthritis and spondyloarthritis associated diseases.
The purpose of this study is to determine how the body's immune system interacts with nuts and other foods to cause allergic reaction. This study also plans to validate a test that is being developed to help predict reactions to peanuts.