An Open-label Extension Study for Participants who Completed Study IMVT-1401-3201 or Study IMVT-1401-3202 to Assess the Efficacy and Safety of Batoclimab for the Treatment of Thyroid Eye Disease (TED)
University of Colorado Hospital Study IMVT-1401-3203 is a 2-cohort extension study for eligible participants completing the Week 24 visit on the feeder studies, IMVT-1401-3201 or IMVT-1401-3202. Participants will be assessed as proptosis responders or non-responders at Week 24 in the feeder studies. Based upon this as... |
IMVT-1401-3201: A Phase 3, Multi-center, Randomized, Quadruple-masked, Placebo-controlled Study of Batoclimab for the Treatment of Participants with Active Thyroid Eye Disease (TED)
University of Colorado Hospital Study IMVT-1401-3201 is a Phase 3, multi-center, randomized, quadruple‑masked (Sponsor, Investigator, assessor, and participant), placebo‑controlled study was designed to assess the efficacy and safety of batoclimab in adult participants with active, moderate to severe TED. The study durat... |
An Observational Study in Subjects to Follow the Progression of
Stargardt Disease Type 1 (STGD1) Caused by Bi-Allelic
Autosomal Recessive Mutations in the ATP Binding Cassette
Subfamily A Member 4 (ABCA4) Gene
(POLARIS)
University of Colorado Hospital This is a prospective, observational, non-interventional, multi-center, global clinical study of subjects with early to advanced stage STGD1 caused by bi-allelic likely pathogenic or pathogenic variants in the ABCA4 gene, confirmed genotypically by an accredited genotyping laboratory. T... |
A STUDY TO EVALUATE THE SAFETY AND EFFICACY OF KPI-012 OPHTHALMIC SOLUTION IN PARTICIPANTS WITH PERSISTENT CORNEAL EPITHELIAL DEFECT (PCED)
University of Colorado Hospital PCED is a persistent non-healing corneal defect or wound that does not heal with traditional treatments. There are many causes of PCED including mechanical trauma, corneal dryness, neurotrophic disease, post-surgical changes, and infection. In patients with PCED, the corneal epithelium (ou... |
Stress Response to Glaucoma Visual Field Testing
Outpatient CTRC, University of Colorado Hospital The primary outcome measures will be change in heart rate, blood pressure, salivary cortisol levels, and state anxiety pre- and post-visual field testing and the difference in these responses between HVF and VRVF... |