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An Open-label Extension Study for Participants who Completed Study IMVT-1401-3201 or Study IMVT-1401-3202 to Assess the Efficacy and Safety of Batoclimab for the Treatment of Thyroid Eye Disease (TED)
University of Colorado Hospital Study IMVT-1401-3203 is a 2-cohort extension study for eligible participants completing the Week 24 visit on the feeder studies, IMVT-1401-3201 or IMVT-1401-3202. Participants will be assessed as proptosis responders or non-responders at Week 24 in the feeder studies. Based upon this as... |
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IMVT-1401-3201: A Phase 3, Multi-center, Randomized, Quadruple-masked, Placebo-controlled Study of Batoclimab for the Treatment of Participants with Active Thyroid Eye Disease (TED)
University of Colorado Hospital Study IMVT-1401-3201 is a Phase 3, multi-center, randomized, quadruple‑masked (Sponsor, Investigator, assessor, and participant), placebo‑controlled study was designed to assess the efficacy and safety of batoclimab in adult participants with active, moderate to severe TED. The study durat... |
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A Multicenter Phase 2b Randomized, Double-Masked, Placebo-Controlled Dose-Ranging Study of TOUR006 in Participants with Thyroid Eye Disease
University of Colorado Hospital The purpose of this dose ranging study is to study the efficacy and safety of TOUR006 SC compared with placebo in participants with moderate to severe TED.... |
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A MULTICENTER, RANDOMIZED, DOUBLE-MASKED, SHAM-CONTROLLED,
PARALLEL-GROUP PHASE 3 STUDY TO EVALUATE THE EFFICACY AND
SAFETY OF EPITHELIUM-ON CORNEAL CROSS-LINKING IN SUBJECTS 8 TO
45 YEARS OF AGE WITH KERATOCONUS (APRICITY-B)
University of Colorado Hospital To evaluate the efficacy of the riboflavin-sodium iodide solution followed by ultraviolet A (UVA) exposure and epithelium-on corneal crosslinking (CXL) assessed by visual acuity measurement in subjects with keratoconus.... |
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A multicenter, observational study to evaluate corneal neurosensory abnormalities in patients with Sjogren's dry eye
University of Colorado Hospital This clinical study has been designed to evaluate the proportion of patients with confirmed Sjogren's dry eye who present with neurosensory abnormalities via demonstration of increased ocular pain and/or a decrease in corneal sensitivity.... |
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An Observational Study in Subjects to Follow the Progression of
Stargardt Disease Type 1 (STGD1) Caused by Bi-Allelic
Autosomal Recessive Mutations in the ATP Binding Cassette
Subfamily A Member 4 (ABCA4) Gene
(POLARIS)
University of Colorado Hospital This is a prospective, observational, non-interventional, multi-center, global clinical study of subjects with early to advanced stage STGD1 caused by bi-allelic likely pathogenic or pathogenic variants in the ABCA4 gene, confirmed genotypically by an accredited genotyping laboratory. T... |
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A STUDY TO EVALUATE THE SAFETY AND EFFICACY OF KPI-012 OPHTHALMIC SOLUTION IN PARTICIPANTS WITH PERSISTENT CORNEAL EPITHELIAL DEFECT (PCED)
University of Colorado Hospital PCED is a persistent non-healing corneal defect or wound that does not heal with traditional treatments. There are many causes of PCED including mechanical trauma, corneal dryness, neurotrophic disease, post-surgical changes, and infection. In patients with PCED, the corneal epithelium (ou... |