The global aim of this pilot study is to determine whether estrogen plus spironolactone increases levels of certain biomarkers of coagulation and thrombosis in trans women or other persons taking estrogen plus spironolactone for feminizing Gender Affirming Hormone Therapy after six months and twelve months.
We are enrolling transgender women who are starting feminizing Gender Affirming Hormone Therapy (e.
g., estrogen plus spironolactone). They are adults who were assigned male at birth but whose gender identity is female.
Main Procedures Involved: Measuring plasma for certain biomarkers of coagulation and thrombosis at baseline and after six months and twelve months of taking estradiol plus spironolactone.
Duration of Participation: 12 months.
Pilot - A pilot Study is used to obtain information, and work out the logistics and management, deemed necessary for further Research Studies.
University of Colorado Hospital
Protocol Number: 20-0104
Not finding the right Study for you? Join ResearchMatch, a nation-wide registry connecting volunteers and researchers