This research study plans to examine the effects of an investigational new drug on neuronal, physiological, and behavioral mechanisms of obesity in the general population.
This study plans to learn more about the effects of an investigational new drug (DMXB-A) and its effects on obesity. The study drug has similar effects to nicotine. Since nicotine has been found to effect appetite, we are interested in studying the effects of the study drug, which has similarities to nicotine, on how your brain responds to such things as pictures of food. This study drug has not been approved by the Food and Drug Administration (FDA), and is considered experimental.More
BMI greater than 27; Be 21-65 years old; Have no known cardiovascular disease; Be a non-smoker; Not be pregnant or trying to conceive; Be able to complete an MRI scan.
I - Research Studies that focus on the safety of a drug. The goal is to determine the drug's most frequent and serious adverse events and, often, how the drug is broken down and excreted by the body. These studies usually involve a small number of participants.
University of Colorado Hospital
Jason Tregellas, PhD
Protocol Number: 15-0650
More information available at ClinicalTrials.gov: NCT02458313
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